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Symbol Name ID |
Drosha
drosha, ribonuclease type III MGI:1261425 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
blood vessel inflammation |
intestinal inflammation |
decreased thymocyte number |
enlarged spleen |
decreased double-positive T cell number |
increased granulocyte number |
decreased CD8-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
increased gamma-delta T cell number |
decreased regulatory T cell number |
increased activated T cell number |
decreased lymphocyte cell number |
increased leukocyte cell number |
abnormal regulatory T cell morphology |
abnormal T cell activation |
enlarged lymph nodes |
abnormal immune system physiology |
abnormal interferon-gamma secretion |
abnormal interleukin-4 secretion |
liver inflammation |
lung inflammation |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Droshatm1Litt/Droshatm1.1Litt Foxp3tm4(YFP/icre)Ayr/Foxp3tm4(YFP/icre)Ayr (conditional) |
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| Droshatm1Litt/Droshatm1.1Litt Tg(Cd4-cre)1Cwi/0 (conditional) |
* | ||||||||||||||||||||||
| Droshatm1Litt/Droshatm1.1Litt Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+ (conditional) |
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| Droshatm1Litt/Droshatm1.1Litt Foxp3tm4(YFP/icre)Ayr/Y (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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